When it comes to key ingredients, Missouri can’t be certain lately when a vital piece in its recipe for winning is available.Tigers quarterback Brady Cook left each of the last two games due to different injuries.Coming off a bye week, though, head coach Eli Drinkwitz is hopeful Cook can return when No. 24 Missouri plays Oklahoma on Saturday in Columbia, Mo.Cook figures to be listed as either “probable” or “doubtful” for the matchup with the Sooners, as he was ahead of the 34-0 loss to Alabama on Oct. 26.He played in that game, though suffered an apparent hand injury after completing 7 of 12 passes.With Cook, the Tigers offense has been dynamic.”He’s got great juice and just, he’s fearless,” Oklahoma coach Brent Venables said of Cook. “I don’t know his entire background, but he’s a winner. I think he brings out the best in the players around him. … You can see the guts and the toughness.”If Cook can’t go, Drinkwitz said Drew Pyne would start for Missouri (6-2, 2-2 SEC).Pyne came on in relief of Cook against both Auburn and Alabama, throwing three interceptions in the loss to the Crimson Tide.”We put him in some bad situations,”Drinkwitz said of Pyne. “We’ve got to protect better. We’ve got to establish the run better and can’t turn the ball over.”Saturday’s meeting will be the first between the Tigers and Sooners in the SEC.The teams were longtime rivals in the Big 12 and Big Eight, meeting 96 times during their history, with Oklahoma leading 67-24-5.The teams met in back-to-back Big 12 Championship Games in 2007 and 2008 before the Tigers moved to the SEC in 2012.Venables was the Sooners’ defensive coordinator for those games.