San Diego Padres right-hander Yu Darvish will open the regular season on the injured list with elbow inflammation after he was shut down with arm fatigue earlier in the week.

The Padres face the Atlanta Braves at home on March 27 to begin the 2025 season.

San Diego right-hander Michael King already has been announced as the team’s Opening Day starter. Darvish was the Padres’ starter in the season opener last season.

Darvish has made two Cactus League starts this spring, going 1-0 with a 4.05 ERA in 6 2/3 innings. He went 2 2/3 innings in a March 8 start against the Guardians, then went four innings in a March 13 outing against the Kansas City Royals, while throwing 54 pitches.

Darvish made just 16 starts in 2024 as he went through elbow soreness, along with hip and neck issues. He was 7-3 with a 3.31 ERA in 81 2/3 innings and was solid in the playoffs when he went 1-1 with a 1.98 ERA in two starts of an eventual series loss to the Dodgers.

In 12 major league seasons, Darvish is 110-88 with a 3.58 ERA in 282 starts for the Texas Rangers (2012-2017), Dodgers (2017), Chicago Cubs (2018-20) and Padres. The five-time All-Star was a runner up in the American League Cy Young Award voting in 2013.