Andy Ibanez hit a three-run homer, Casey Mize pitched six strong innings and the host Detroit Tigers extended their winning streak to four games with a 6-2 victory over the New York Yankees on Monday.

Justyn-Henry Malloy supplied a two-run single for Detroit, which has won six of its last seven games. Jake Rogers and Colt Keith scored two runs apiece.

Mize limited the Yankees to one run and four hits in six innings while recording six strikeouts. Tyler Holton, Beau Brieske and Tommy Kahnle each tossed an inning of scoreless relief.

Yankees starter Carlos Rodon gave up six runs, five earned, on four hits with eight strikeouts in six-plus innings. Aaron Judge had an RBI single for New York, which managed just one extra-base hit in the chilly conditions.

Reds 2, Giants 0

Hunter Greene came within one out of a complete-game shutout, Blake Dunn ended a scoreless deadlock with a two-run double in the eighth inning, and Cincinnati ended host San Francisco’s seven-game winning streak with a victory in the opener of a three-game series.

Greene (1-1), who had never previously pitched more than 7 1/3 innings in his career, allowed just three hits and no walks until Jung Hoo Lee singled with two outs in the ninth and Matt Chapman followed with a full-count walk. Reds manager Terry Francona pulled his right-hander at that point. The combined shutout was the fourth of Greene’s career. He struck out seven.

Logan Webb matched Greene zero for zero until getting pulled after seven innings. Webb allowed just four hits, all singles. He struck out 10 without issuing a walk.

Nationals 6, Dodgers 4

MacKenzie Gore threw six quality innings, James Wood hit a two-run home run and Washington earned a win over visiting Los Angeles.

Gore (1-1) allowed two runs as the Nationals won their third in a row in the opener of a three-game series.

Dustin May (0-1) gave up three runs (one earned) over six innings for the Dodgers. Shohei Ohtani went 3-for-4 with a two-run homer and was a double shy of hitting for the cycle.

Royals 4, Twins 2

Kyle Isbel went 3-for-4 with a homer and two RBIs to lead Kansas City past visiting Minnesota.

Michael Lorenzen (1-1) allowed one run and five hits in six innings as the Royals won for the third time in four games. Carlos Estevez yielded a run in the ninth but got his third save.

Willi Castro and Harrison Bader each drove in a run for the Twins, who lost for the third time in four games. Bader and Matt Wallner had two hits apiece for Minnesota. Simeon Woods Richardson (0-1) was touched up for four runs over 5 2/3 innings.

Mets 2, Marlins 0

Kodai Senga and three relievers combined on a seven-hit shutout for host New York, which continued its stingy ways against Miami.

Juan Soto and Tyrone Taylor each had an RBI hit for the Mets, who have won five straight — a span in which they’ve allowed just eight runs. The shutout Monday was the second in the last four games for New York, which leads the majors with a 1.72 ERA.

Senga (1-1) gave up five hits and two walks while striking out four over five innings. He induced double plays in the fourth and fifth.

Pirates 8, Cardinals 4

Joey Bart hit a home run and an RBI triple to help host Pittsburgh defeat St. Louis and secure back-to-back wins for the first time this season.

The Pirates’ eight runs were a season high. Andrew McCutchen, Isiah Kiner-Falefa and Endy Rodriguez joined Bart in going 2-for-4.

Pirates rookie Thomas Harrington, who started on April 1, changed roles and tossed a four-inning save. According to the Pirates’ broadcast, it was the third four-inning save by a rookie in Pirates history, joining Kent Tekulve and Blas Minor.

Padres 5, Athletics 4

Jake Cronenworth and Fernando Tatis Jr. homered while Manny Machado knocked in two runs as San Diego held off the Athletics in West Sacramento, Calif.

Michael King (2-0) allowed eight hits and three runs over 5 2/3 innings. Four relievers covered the final 10 outs, with Robert Suarez pitching the ninth for his fifth save in as many chances.

Tyler Soderstrom hit two solo homers, and he is tied for the major league home run lead with six. Luis Severino (0-2) permitted eight hits and five runs in seven innings.

Blue Jays 6, Red Sox 2

George Springer went 4-for-4 with three two-out RBIs and Jose Berrios spun seven strong innings to lead visiting Toronto to a win over Boston in the opener of a four-game series.

Springer contributed to all four run-scoring innings and led a 13-hit attack for the Blue Jays, who had lost three straight. Berrios (1-1) induced nine groundouts and struck out two to complete his outing on 88 pitches despite allowing one run on four hits and three walks.

Jarren Duran had two of Boston’s five hits. The Red Sox were on a five-game win streak. Starter Richard Fitts (0-2) departed after six innings of three-run ball. He permitted six hits and four walks while striking out four.

Cubs 7, Rangers 0

Michael Busch, Kyle Tucker and Seiya Suzuki had two hits each and Justin Steele allowed just three hits over seven innings as host Chicago rolled to a win over Texas in the first of a three-game interleague series.

Steele (3-1) was masterful, allowing three singles and two walks while striking out eight as the Cubs dominated throughout. Colin Rea pitched the final two innings and did not allow a baserunner while striking out one. Ian Happ drove in three runs out of the leadoff spot.

Nathan Eovaldi (1-1) took the loss for the Rangers after allowing three runs on four hits in 4 2/3 innings. He was followed to the mound by Gerson Garabito, who surrendered four runs on six hits over 3 1/3 innings. Kyle Higashioka had two of the three hits for the Rangers, who had a five-game winning streak snapped.

Mariners 4, Astros 3

Jorge Polanco’s two-run single with two outs in the bottom of the eighth capped an eventful inning as Seattle rallied to defeat visiting Houston in the opener of a three-game series.

The Mariners entered the eighth with a 2-1 lead after a pitching duel between Houston’s Hayden Wesneski and fellow right-hander Logan Gilbert of Seattle. But the Astros scored twice thanks in part to a wild pitch, a pair of walks and an error that allowed the runs to score.

But the Mariners put the first two batters on in the bottom of the eighth before Polanco then lined a slider off pitcher Byan Abreu’s glove and into center field to score the tying and go-ahead runs.

Orioles 5, Diamondbacks 1

Ryan O’Hearn had two hits including a homer, and Gunnar Henderson had two hits, two runs and two stolen bases as Baltimore won in Phoenix to hand Arizona its third straight loss.

Ryan Mountcastle had a two-run single and Zach Eflin (2-1) gave up one run in six innings in his third quality start of the season for the Orioles, who had lost four of five.

Arizona starter Zac Gallen (1-2) gave up five runs on seven hits in 4 2/3 innings, with four walks and two strikeouts. He has walked four in both of his home starts this season.