Missouri quarterback Brady Cook will miss Saturday’s contest against visiting Oklahoma due to ankle and wrist injuries.Cook’s status was in doubt all week but the school downgraded him to out on Friday’s Southeastern Conference injury report.The missed contest will end Cook’s streak of 35 consecutive starts. He ranks fourth in school history with 8,053 career passing yards and sits fifth with 45 touchdown passes.Drew Pyne will start in place of Cook for the No. 24 Tigers (6-2, 2-2 SEC), who are coming off a bye.Cook has passed for 1,575 yards and seven touchdowns in eight games this season. He has thrown just one interception in 218 attempts. He also has rushed for four touchdowns.